Dr  Alan  Ironmonger

Alan Ironmonger graduated with a first class MChem from the University of Leeds in 2001, and took up a position on the prestigious Wellcome Trust 4-year PhD scheme at Leeds.  Alan prepared libraries of stereochemically diverse, complex aminoglycosides which were used to study the function of RNAs such as the HIV sequences, RRE and TAR, and the thiostrepton binding site of the prokaryotic ribosome.  Alan was jointly supervised by Professor Peter Stockley.  Alan moved to a postdoctoral position in Professor Tim Donohoe's laboratory at the University of Oxford.  Alan is now a synthetic chemist at GSK.

Publications with Professor Nelson:

63 Chris  Adams, Alison  Ashcroft, Andy  Baron, Blandine  Clique , Alan  Ironmonger , Adam  Nelson , Peter  Stockley and Ben  Whittaker , "Scanning conformational space with a library of stereo- and regiochemically diverse aminoglycoside derivatives: The discovery of new ligands for RNA hairpin sequences", Org. Biomol. Chem. 2007, 5, 1081-1086
Open Access Version
Keywords: "Stereochemically diverse libraries" "Chemical Genetics"

54 Simon  Barrett , Steve  Bartlett , Amanda  Bolt , Alan  Ironmonger , Catherine  Joce , Adam  Nelson and Thomas  Woodhall , "Configurational stability of bisindolylmaleimide cyclophanes: From conformers to the first configurationally stable, atropisomeric bisindolylmaleimides", Chem. Eur. J. 2005, 11, 6277-6285
Open Access Version
Keywords: "Stereochemically diverse libraries"

50 Blandine  Clique , Jackie  Colley , Alan  Ironmonger , Adam  Nelson , Peter  Stockley, James  Titchmarsh and Ben  Whittaker , "Synthesis of a library of stereo- and regiochemically diverse aminoglycoside derivatives", Org. Biomol. Chem. 2005, 3, 2776-2785
Open Access Version - provided courtesy of the RSC
Keywords: "Stereochemically diverse libraries" "Chemical Genetics"

48 Alan  Ironmonger , Adam  Nelson and Peter  Stockley, "Asymmetric double ring-opening of a C2h-symmetric bisepoxide: Improved enantiomeric excess of the product through enantioselective desymmetrisation and ‘proof-reading’ steps", Org. Biomol. Chem. 2005, 3, 2350-2353
Open Access Version - provided courtesy of the RSC
Keywords: "New strategies for asymmetric synthesis"

Research areas

Chemical Genetics

New strategies for asymmetric synthesis

Stereochemically diverse libraries