Dr Stuart Warriner
0113 343 6437
Stuart Warriner is a member of the School of Chemistry and the Astbury Centre at the University of Leeds. We collaborate with him on a number of projects, particularly those involving solid-supported organic synthesis. For more details of his research, see his web site.
Publications with Professor Nelson:
129 |
Katherine Abrahams, Del Besra, Mark Dow
, Adam Nelson
, Luis Vaz and Stuart Warriner
,
"Modular Synthesis of Diverse Natural Product-like Macrocycles: Discovery of Hits with Antimycobacterial Activity", Chem. Eur. J. 2017, 23, 7207-7211
Keywords: "Chemical Genetics" "Diversity-oriented synthesis" |
120 |
Alex Breeze
, George Burslem
, Thomas Edwards
, Hannah Kyle
, Adam Nelson
, P Prabhakaran, Stuart Warriner
and Andrew Wilson
,
"Synthesis of highly functionalised oligobenzamide proteomimetic foldamers by late stage introduction of sensitive groups", Org. Biomol. Chem. 2016, 14, 3782-3786
Keywords: "Chemical Genetics" |
119 |
Alex Breeze
, George Burslem
, Thomas Edwards
, Hannah Kyle
, Adam Nelson
, Stuart Warriner
and Andrew Wilson
,
"Towards ‘bionic’ proteins: replacement of continuous sequences from HIF-1alpha with proteomimetics to create functional p300 binding HIF-1alpha mimics", Chem. Commun. 2016, 52, 5421-5424
Keywords: "Chemical Genetics" |
116 |
Anthony Aimon
, Mark Dow
, George Karageorgis
, Adam Nelson
and Stuart Warriner
,
"Activity-directed Synthesis with Intermolecular Reactions: Development of a Fragment into a Range of Androgen Receptor Agonists", Angew. Chem. Int. Ed. 2015, 54, 13538-13544
Keywords: "Diversity-oriented synthesis" |
114 |
James Firth
, Richard Foster
, Rachel Guilleux, Tuomo Kalliokoski, Steve Marsden
, Remy Morgantin
, Adam Nelson
, Stuart Warriner
and Rong Zhang
,
"Exploitation of the Ugi-Joullié reaction in the synthesis of libraries of drug-like bicyclic hydantoins", Synthesis 2015, , 2391-2406
Keywords: "Diversity-oriented synthesis" |
113 |
Alex Breeze
, George Burslem
, Thomas Edwards
, Hannah Kyle
, Adam Nelson
, Jonathan Stott, Darren Tomlinson
, Stuart Warriner
, Kate Wickson and Andrew Wilson
,
"Exploration of the HIF-1alpha/p300 binding interface using peptide and adhiron phage display technologies to locate binding hot-spots for inhibitor development", Mol. Biosys. 2015, 11, 2738-2749
Keywords: "Chemical Genetics" |
107 |
George Karageorgis
, Adam Nelson
and Stuart Warriner
,
"Efficient discovery of bioactive scaffolds by activity-directed synthesis", Nature Chem. 2014, 6, 872-876
Keywords: "Diversity-oriented synthesis" |
105 |
Alex Breeze
, George Burslem
, Thomas Edwards
, Hannah Kyle
, Adam Nelson
, Stuart Warriner
and Andrew Wilson
,
"Small Molecule Proteomimetic Inhibitors of the HIF-1alpha/p300 Protein-Protein Interaction", ChemBioChem 2014, 14, 1083-1087
Keywords: "Chemical Genetics" |
104 |
George Burslem
, Andrew Grant
, Tom James
, Paul MacLellan
, Adam Nelson
, Iain Simpson
, Sri Sridharan
and Stuart Warriner
,
"A modular lead-oriented synthesis of diverse piperazine, 1,4-diazepane and 1,5-diazocane scaffolds", Org. Biomol. Chem. 2014, 12, 2584-2591
Keywords: "Diversity-oriented synthesis" |
102 |
Sandra Bell, Jackie Bond, Julie Higgins, Heather Martin
, Ewan Morrison, Adam Nelson
, Darren Tomlinson
and Stuart Warriner
,
"High-Content, High-Throughput Screening for the Identification of Cytotoxic Compounds Based on Cell Morphology and Cell Proliferation Markers", Plos ONE 2014, 9, e88338
Keywords: "Chemical Genetics" |
96 |
Mark Dow
, Sushil Maurya
, Adam Nelson
and Stuart Warriner
,
"Synthesis of skeletally diverse alkaloid-like molecules: exploitation of metathesis substrates assembled from triplets of building blocks", Beil. J. Org. Chem. 2013, 9, 775-785
Keywords: "Diversity-oriented synthesis" |
90 |
Catherine Joce
, Adam Nelson
, Peter Stockley, Stuart Warriner
and Rebecca White,
"Design, Synthesis and In Vitro Evaluation of Novel Bivalent S-Adenosylmethionine Analogues", Bioorg. Med. Chem. Lett. 2012, 22, 278-284
Keywords: "Chemical Genetics" |
77 |
Chris Cordier
, Jerome Hayes, Adam Nelson
, Catherine O'Leary-Steele
and Stuart Warriner
,
"A fluorous-tagged Safety Catch Linker for Preparing Heterocycles by Ring-Closing Metathesis", Org. Lett. 2009, 11, 915-918
Keywords: "Diversity-oriented synthesis" |
76 |
Steve Bartlett
, Christian Einzinger
, David Glowacki
, Ben McKeever-Abbas
, Sarah Murrison
, Adam Nelson
, James Titchmarsh
and Stuart Warriner
,
"Remarkably slow rotation about a single bond between an sp3-hybridised carbon and an aromatic ring without ortho substituents", Chem. Eur. J. 2009, 15, 2185-2189
Keywords: "Diversity-oriented synthesis" |
75 |
Jamie Caryl
, Catherine Joce
, Adam Nelson
, Peter Stockley and Stuart Warriner
,
"Identification of stable S-adenosylmethionine (SAM) analogues derivatised with bioorthogonal tags: Effect of ligands on the affinity of the E. coli methionine repressor, MetJ, for its operator DNA", Org. Biomol. Chem. 2009, 7, 635-638
Keywords: "Chemical Genetics" |
74 |
Chris Cordier
, Stuart Leach
, Daniel Morton
, Adam Nelson
and Stuart Warriner
,
"Synthesis of natural product-like molecules with over eighty distinct skeletons", Angew. Chemie. Int. Ed. 2009, 48, 104-109
Keywords: "Chemical Genetics" "Diversity-oriented synthesis" |
71 |
Chris Cordier
, Stuart Leach
, Daniel Morton
, Adam Nelson
, Catherine O'Leary-Steele
, Stuart Warriner
and Thomas Woodhall
,
"An efficient method for synthesising unsymmetrical silaketals: substrates for ring-closing, including macrocycle-closing, metathesis", Org. Biomol. Chem. 2008, 6, 1734-1737
Keywords: "Diversity-oriented synthesis" |
69 |
Chris Cordier
, Stuart Leach
, Gordon McKiernan
, Daniel Morton
, Adam Nelson
and Stuart Warriner
,
"A fluorous-tagged linker from which small molecules are released by ring-closing metathesis", J. Org. Chem. 2008, 73, 2752-2759
Keywords: "Diversity-oriented synthesis" |
52 |
Steve Bartlett
, Godfrey Beddard, Richard Jackson, Veysel Kayser, Colin Kilner
, Andrew Leach, Adam Nelson
, Peter Oledzki, Peter Parker, Gavin Reid and Stuart Warriner
,
"Comparison of the ATP binding sites of Protein Kinases using conformationally diverse bisindolylmaleimides", J. Am. Chem. Soc. 2005, 127, 11699-11708
Keywords: "Stereochemically diverse libraries" "Chemical Genetics" |
19 |
Stuart Green
, Adam Nelson
, Stuart Warriner
and Ben Whittaker
,
"Synthesis and investigation of the configurational stability of some dimethylammonium borate salts", J. Chem. Soc., Perkin Trans. 1 2000, , 4403-4408
Open Access Version - provided courtesy of the RSC |
Research areas