Shiao  Chow

Shiao graduated from the University of Queensland (Australia) in 2009 with a first class honours Bachelor of Biotechnology degree. Her final year research project focused on the development of alpha-helical analgesic peptide mimetics. She commenced her PhD under the supervision of Prof. Dr. David Fairlie. During this time, she worked in the interface of computational modelling, chemistry and biology to develop potent and selective serine protease inhibitors.

Following her PhD, Shiao pursued her postdoctoral study as a Carl Tryggers Research Fellow with Assoc. Prof. Luke Odell at Uppsala University (Sweden). She led several methodology development projects to explore novel chemical transformations focusing on palladium-, photoredox- and radical-mediated carbonylations, including the translation of these methodologies to 11C-radiochemistry. 

Shiao worked on activity-directed synthesis (ADS) of bioactive molecules.  She secured a Marie Curie fellowship that she undertook at the University of Edinburgh.

Publications with Professor Nelson:

141 Shiao  Chow , Joan  Mayol Llinas and Adam  Nelson , "Expansion of the structure-activity relationships of BACE1 inhibitors by harnessing diverse building blocks prepared using a unified synthetic approach", MedChemComm 2019, 10, 616-620
Keywords: "Chemical Genetics"

136 Shiao  Chow , Samuel  Liver and Adam  Nelson , "Streamlining bioactive molecular discovery through integration and automation", Nat. Rev. Chem. 2018, 2, 174-183
Keywords: "Diversity-oriented synthesis"

128 Shiao  Chow and Adam  Nelson , "Embarking on a Chemical Space Odyssey", J. Med. Chem. 2017, 60, 3591-3593
Keywords: "Diversity-oriented synthesis"