Catherine  O'Leary-Steele

Catherine Rourke graduated with a first class MChem degree from the University of Oxford in 2005, completing her part II project under the supervision of Prof. Steve Davies, studying stereoselective enamide functionalisation.

Catherine's PhD was supported by a University Scholarship and a CASE award from GSK, which involved an industrial placement at GSK's Tonbridge site with Dr Jerome Hayes.  Her project was concerned with the synthesis of libraries of skeletally diverse, natural product-like compounds to be used for screening in chemical genetics assays.  Catherine moved onto a postdoctoral position with Dr Stuart Warriner.

Publications with Professor Nelson:

81 Jerome  Hayes, Tom   James , Tom  Lanyon-Hogg , Stuart  Leach , Adam  Nelson , Catherine  O'Leary-Steele and Palle  Pedersen , "Synthesis of Small Molecules with High Scaffold Diversity: Exploitation of Metathesis Cascades in Combination with Inter- and Intramolecular Diels-Alder Reactions", Chem. Eur. J. 2010, , 9563-9671
Keywords: "Diversity-oriented synthesis"

77 Chris  Cordier , Jerome  Hayes, Adam  Nelson , Catherine  O'Leary-Steele and Stuart  Warriner , "A fluorous-tagged Safety Catch Linker for Preparing Heterocycles by Ring-Closing Metathesis", Org. Lett. 2009, 11, 915-918
Keywords: "Diversity-oriented synthesis"

71 Chris  Cordier , Stuart  Leach , Daniel  Morton , Adam  Nelson , Catherine  O'Leary-Steele , Stuart  Warriner and Thomas  Woodhall , "An efficient method for synthesising unsymmetrical silaketals: substrates for ring-closing, including macrocycle-closing, metathesis", Org. Biomol. Chem. 2008, 6, 1734-1737
Keywords: "Diversity-oriented synthesis"

70 Chris  Cordier , Daniel  Morton , Sarah  Murrison , Adam  Nelson and Catherine  O'Leary-Steele , "Natural products as an inspiration in the diversity-oriented synthesis of bioactive compound libraries", Nat. Prod. Rep. 2008, , 719-737
Keywords: "Chemical Genetics" "Diversity-oriented synthesis"

Research areas

Diversity-oriented synthesis

Stereochemically diverse libraries