Dr  Stuart  Leach

Stuart graduated with a first class MChem degree from the University of Durham
in 2004, winning the BP Chemicals Prize for the top mark in the year, as well
as winning the Huntsman-Tioxide Scholarship in third year and the Organic
Chemistry Prize in second year.

His undergraduate degree involved a fourth year project working with Dr John
Sanderson on the synthesis of tryptophan analogues. He also carried out a
summer internship at GSK's Harlow site.

Stuart's PhD was supported by the EPSRC. His project was concerned with the
synthesis of libraries of alkaloid-like unnatural products, which will be used
for screening in chemical genetics assays. Stuart had a short postdoctoral stint within the group before joining GSK as a senior scientist.

Publications with Professor Nelson:

81 Jerome  Hayes, Tom   James , Tom  Lanyon-Hogg , Stuart  Leach , Adam  Nelson , Catherine  O'Leary-Steele and Palle  Pedersen , "Synthesis of Small Molecules with High Scaffold Diversity: Exploitation of Metathesis Cascades in Combination with Inter- and Intramolecular Diels-Alder Reactions", Chem. Eur. J. 2010, , 9563-9671
Keywords: "Diversity-oriented synthesis"

74 Chris  Cordier , Stuart  Leach , Daniel  Morton , Adam  Nelson and Stuart  Warriner , "Synthesis of natural product-like molecules with over eighty distinct skeletons", Angew. Chemie. Int. Ed. 2009, 48, 104-109
Keywords: "Chemical Genetics" "Diversity-oriented synthesis"

71 Chris  Cordier , Stuart  Leach , Daniel  Morton , Adam  Nelson , Catherine  O'Leary-Steele , Stuart  Warriner and Thomas  Woodhall , "An efficient method for synthesising unsymmetrical silaketals: substrates for ring-closing, including macrocycle-closing, metathesis", Org. Biomol. Chem. 2008, 6, 1734-1737
Keywords: "Diversity-oriented synthesis"

69 Chris  Cordier , Stuart  Leach , Gordon  McKiernan , Daniel  Morton , Adam  Nelson and Stuart  Warriner , "A fluorous-tagged linker from which small molecules are released by ring-closing metathesis", J. Org. Chem. 2008, 73, 2752-2759
Keywords: "Diversity-oriented synthesis"

66 Chris  Cordier , Stuart  Leach and Adam  Nelson , "1,3-Dioxetanes and 1,3-Dioxolanes", Science of Synthesis ed. S. Warriner, 2007, 29, 407-486

Research areas

Natural product synthesis