Dr  James  Howard

J.K.Howard@leeds.ac.uk

36436


James obtained his Bachelor of Science with Honours in 2010 at the University of Tasmania, Australia. Returning the following year, he began his PhD studies under the joint supervision of Dr. Jason Smith, Dr. Christopher Hyland and Dr. Alex Bissember. His project was devoted to the development of new methodologies in organic synthesis with two main focuses: the oxidative dearomatisation of pyrroles, and the strain driven rearrangement of cyclopropenes.

James joined the Nelson group as a postdoctoral research fellow in 2015 and was co-supervised by Professor Alan Berry. He was employed on the EU's IMI-funded project, CHEM21, and his project involved exploiting aldolase enzymes as biocatalysts for the stereoselective synthesis of fluorine containing small molecules.

Publications with Professor Nelson:

121 Alan  Berry , James  Howard , Marion  Muller and Adam  Nelson , "An enantio- and diastereoselective chemoenzymatic synthesis of alpha-fluoro beta-hydroxy carboxylic esters", Angew. Chem. Int. Ed. 2016, 55, 6767-6770
Keywords: "Directed evolution"

Research areas

Directed evolution