Adam  Daniels

Adam was a BBSRC-funded student who is jointly supervised by Dr Alan Berry and Professor Adam Nelson.  His project concerned understanding how enzymes control the stereochemical course of C-C bond formation, and evolving enzymes which allow the preparation of stereoisomeric products.

Publications with Professor Nelson:

117 Alan  Berry , Adam  Daniels , Tom  Harman , Tomas  Lebl, Keith   Mullholland, Adam  Nelson , Arwen  Pearson, Jennifer  Stockwell , Chi  Trinh , Claire  Windle and Thomas  Woodhall , "Evaluation of fluoropyruvate as nucleophile in reactions catalysed by N-acetyl neuraminic acid lyase variants: scope, limitations and stereoselectivity", Org. Biomol. Chem. 2015, , in press
Keywords: "Directed evolution"

101 Alan  Berry , Amanda  Bolt , Ivan  Campeotto , Adam  Daniels , Adrian   Mulholland , Adam  Nelson , Arwen  Pearson , Simon  Phillips and Marc  van der Kamp , "The reaction mechanism of N-acetylneuraminic acid lyase revealed by a combination of crystallography, QM/MM simulation and mutagenesis", ACS Chem. Biol. 2014, 9, 1025-1032
Keywords: "Directed evolution"

92 Alan  Berry , Adam  Daniels , Adam  Nelson and Nicole  Timms , "Directed Evolution and (Semi-) Rational Design Strategies for the Creation of Synthetically Useful, Stereoselective Biocatalysts", Comprehensive Chirality 2012, , in press
Keywords: "Directed evolution"

Research areas

Directed evolution