Dr  Heather  Bone

Heather was based in Melanie Welham's laboratory at the University of Bath.  Heather was involved in a project led by Professors Welham and Nelson which used a chemical genetic approach to determine the molecular mechanisms that underpin murine embryonic stem cell self-renewal.

Publications with Professor Nelson:

87 Heather  Bone , Adam  Nelson and Melanie  Welham, "A novel chemically directed route for the generation of definitive endoderm from human embryonic stems cells based on inhibition of GSK-3", J. Cell Sci. 2011, 124, 1992-2000
Keywords: "Chemical Genetics"

73 Steve  Bartlett , Heather  Bone , Teresa  Damiano , Julie  Letchford , Adam  Nelson , Alexis  Perry and Melanie  Welham, "Involvement of glycogen synthase kinase-3 in regulation of murine embryonic stem cell self-renewal revealed by a series of bisindolylmaleimides", Chem. Biol. 2008, 16, 15-27
Keywords: "Chemical Genetics"

62 Craig  Beck, Heather  Bone , Pierre-Yves   Bourillot, Teresa  Damiano , Adam  Nelson , Pierre  Savatier, Valerie  Schreiber, Mike   Storm and Melanie  Welham, "Regulation of Nanog expression by phosphoinositide 3-kinase-dependent signalling in murine embryonic stem cells ", J. Biol. Chem. 2007, 282, 6265-6273
Open Access Version - provided courtesy of, and copyright held by, the American Society of Biochemistry and Molecular Biology
Keywords: "Chemical Genetics"

Research areas

Chemical Genetics