News

RSC book co-edited by Adam published

Adam has co-edited a book that has been published by the Royal Society of Chemistry (with Nick Westwood, St Andrews).  The book covers complementary approaches to the synthesis of many different classes of biomolecule: from fragments to large macromolecular complexes.  The book includes a chapter describing function-directed discovery approaches such as activity-directed synthesis that has been developed within the group.


Related research

Chemical Genetics Diversity-oriented synthesis

Related publications

138 Adam  Nelson and Nicholas  Westwood, "Chemical and Biological Synthesis: Enabling Approaches for Understanding Biology", Royal Society of Chemistry 2018, ,  ISBN: 978-1-78262-948-1
Keywords: "Chemical Genetics" "Diversity-oriented synthesis"

Related people

Samuel Liver Jacob Masters Adam Nelson Nicholas Westwood

Group day out in the Holme Valley

At the end of August, the group enjoyed a walk in the Holme Valley.  We returned to Adam's house to celebrate the award of the 2018 UCB-Ehrlich award!




Related research

Chemical Genetics Directed evolution Diversity-oriented synthesis Natural product synthesis New strategies for asymmetric synthesis Stereochemically diverse libraries

2018 UCB-Ehrlich award

Adam received the 2018 UCB-Ehrlich award at the European Federation of Medicinal Chemistry's biennial Internation Symposium in Medicinal Chemistry in Ljubljana, Slovenia.  The award recognises his vision to develop chemical approaches that align with discovery needs; and the uptake the approaches in medicinal chemistry programmes.

Related research

Diversity-oriented synthesis

Leeds Postgraduate Symposium 2018

Congratulations to our PhD students Bobby and Chloe for winning the talk and poster prizes at the postgraduate symposium. Well done!


Related people

Bobby Lowe Chloe Townley

PhD Viva

Congratulations to our 4th year PhD student Joan for passing his PhD viva! Joan will be continuing work in the group for the next few months before moving on, so it is not goodbye just yet!


Related people

Joan Mayol Llinas

Astbury Conversation 2018

The University of Leeds recently held the biennial Astbury Conversation on Allostery in Biology; the plenary lecture was given by Nobel Laureate Brian Kobilka. Members of the Nelson group were involved in activities over the two days. Adam Nelson gave a talk entitled 'nature-inspired approaches for bioactive small molecule discovery'. Members of the ADS team took part in a public engagement event with local school children which included a game representing the principles of ADS. On the whole a great two days of science!


Related people

Chris Arter Shiao Chow Adam Green Abbie Leggott Samuel Liver Jacob Masters Adam Nelson Luke Trask Stuart Warriner

Adam wins 2018 UCB-Ehrlich prize



Adam Nelson has been awarded the European Federation for Medicinal Chemistry’s 2018 UCB-Ehrlich Award for Excellence in Medicinal Chemistry. The biennial award recognises his implementation of a vision for new chemical synthesis methods to align with drug discovery needs. His team and collaborators have recently developed new approaches (including lead-oriented and activity-directed synthesis) that enable new bioactive molecules to be discovered.

Related research

Diversity-oriented synthesis